Mopidy www.mopidy.com
No last.fm support yet it seems (universally).

"Stream music from the cloud Vanilla Mopidy only plays music from your local disk and radio streams. Through extensions, Mopidy can play music from cloud services like Spotify, SoundCloud, and Google Play Music. With Mopidy's extension support, backends for new music sources can be easily added." #!TO_TAG_bit #music #aggregated_cloud #aggregating #open_source #python #cross-platform #interesting #unique_spin #personal #pub